Dopamine & Motivation Boost

Bupropion IR

Immediate-release bupropion for depression and smoking cessation support.

Bupropion IR is a prescription antidepressant used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It works differently from typical SSRIs by enhancing norepinephrine and dopamine activity in the brain, which can improve mood, energy, and motivation. It is also sometimes used off-label to support smoking cessation and ADHD management. Immediate-release bupropion is typically dosed multiple times daily for steady symptom control.

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Not sure about dosages? Don't worry, your provider will adjust or confirm your selection after checkout.

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  1. 1

    Place Your Order

    Start by selecting your medication and checking out.You'll be charged for the medical provider review now and for the medication only once it’s approved by the provider.

  2. 2

    Complete a Quick Medical Questionnaire

    After checkout, we need you to answer questions about your symptoms, medical history, and current medications.

  3. 3

    Licensed Provider Review

    A licensed healthcare provider reviews your complete medical profile, ensuring this treatment is safe and appropriate for you.

  4. 4

    Personalized Treatment Plan

    Your provider may recommend an adjustment to your prescription based on your full medical profile before approving your treatment.

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  • Improves symptoms of major depressive disorder within 2–4 weeks of consistent use

  • Increases norepinephrine and dopamine levels to boost mood, focus, and motivation

  • Less likely to cause sexual side effects or weight gain compared to SSRIs

  • May reduce cravings and withdrawal symptoms in smoking cessation therapy

  • Supports energy levels and daytime alertness, making it suitable for patients with fatigue-predominant depression

  • Bupropion HCL: A norepinephrine-dopamine reuptake inhibitor (NDRI) that enhances neurotransmitter levels to improve mood, drive, and cognitive function without significant sedating effects

  • Take by mouth as directed by your provider, typically two to three times daily for IR formulations

  • Space doses at least 6 hours apart to reduce the risk of seizures

  • Do not crush, chew, or split tablets

  • Take consistently at the same time each day for best results

  • If a dose is missed, skip and take the next dose as scheduled – do not double dose