Dual-Action for Depression & Pain

Duloxetine

Dual-Action SNRI for Depression, Anxiety & Chronic Pain

Designed for adults dealing with depression, anxiety, or chronic pain conditions who need comprehensive symptom management. This dual-action antidepressant treats both mood disorders and physical pain by targeting two brain chemicals simultaneously. Perfect for patients with fibromyalgia, diabetic nerve pain, or depression who haven't responded well to single-mechanism medications.

Ingredients dosages:

Frequency:

Quantity:

Not sure about dosages? Don't worry, your provider will adjust or confirm your selection after checkout.

Total

$0.00

Here's what happens next:

  1. 1

    Product checkout

    We'll direct you to our product detail page where you can start the checkout process. You'll be charged for the medical consultation but the medication charge is a hold until the official provider review.

  2. 2

    Comprehensive Medical Questionnaire

    After purchase, you'll be directed to a medical assessment covering your medical history, current medications, and specific symptoms.

  3. 3

    Licensed Provider Review

    A licensed healthcare provider reviews your complete medical profile, ensuring this treatment is safe and appropriate for you.

  4. 4

    Personalized Treatment Plan

    Your provider may recommend an adjustment to your prescription based on your full medical profile before approving your treatment.

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  • Multiple condition treatment: It is FDA-approved for use in the treatment of major depressive disorder, generalized anxiety disorder, fibromyalgia, chronic musculoskeletal pain, and diabetic peripheral neuropathy

  • Dual mechanism advantage: Duloxetine inhibits serotonin and norepinephrine reuptake, thus combining two therapeutic mechanisms in one agent to treat depression and anxiety

  • Pain relief benefits: Enhances serotonergic and adrenergic pain-inhibiting pathways in the spinal cord, raising pain threshold—especially effective in neuropathic pain

  • Fibromyalgia efficacy: 32 studies on major depressive disorder (MDD), 11 studies on GAD, 19 studies on NP, 9 studies on fibromyalgia, and 14 studies on SUI demonstrated that the measured outcomes indicate the suitability of duloxetine in the treatment of these clinical conditions

  • Comprehensive symptom control: Duloxetine is also used in adults to treat nerve pain caused by diabetes (diabetic neuropathy), or chronic muscle or joint pain

  • Duloxetine Hydrochloride: A serotonin and norepinephrine reuptake inhibitor that increases both mood-regulating chemicals while also enhancing pain-blocking pathways in the spinal cord

  • Dosing: Start with 30-60mg once daily, may increase based on condition and response

  • Timing: Take once daily with or without food, preferably at the same time

  • Duration: Allow 2-4 weeks for mood benefits, up to 6-8 weeks for full effect

  • Pain conditions: May see pain improvement within 2 weeks

  • Discontinuation: Must taper gradually under medical supervision to prevent withdrawal