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Topical Formula

MigraCream™

Triple-action topical relief precisely where you need it.

An innovative topical compound that combines three powerful medications (1% Ketoprofen, 4% Lidocaine, 0.5% Metoclopramide) for targeted migraine relief. This fast-absorbing cream delivers medication directly to pain sites while avoiding the digestive system. Perfect for those who prefer targeted treatment or as a complement to oral medications, MigraCream™ provides precise relief through its specialized combination of pain-blocking, anti-inflammatory, and absorption-enhancing ingredients.

Ingredients dosages:

Quantity:

Supply:

Total

$0.00

If you aren’t sure about dosages, make a selection and your provider will help you during the consultation. You won’t be charged for your treatment unless approved by your provider. There is a one-time, non-refundable charge for the provider consultation.

Ketoprofen 1% Metoclopramide 0.5% Lidocaine 4%Ketoprofen 1% Metoclopramide 0.5% Lidocaine 4%

Key Ingredients

Ketoprofen 1%Metoclopramide 0.5%Lidocaine 4%

MigraCream™ offers a unique three-way approach to migraine relief in an easy-to-use topical form. Use this innovative cream for targeted inflammation control, immediate pain relief, and metoclopramide to enhance absorption and help with nausea. Patients appreciate being able to apply relief directly where they need it, avoiding the need to swallow medications when nausea makes that difficult.

The doctor says...

MigraCream™ triple-action formulation allows for precise application exactly where patients need it, while minimizing systemic exposure. For those who experience localized migraine pain or have difficulty tolerating oral medications, this targeted approach can be a game-changer in their treatment plan.
Dr. Alexander Mauskop

Dr. Alexander Mauskop

Hedfirst Chief Medical Advisor

Director, New York Headache Center, Professor of Clinical Neurology, SUNY Downstate Medical Center

Who is MigraCream™ for?

MigraCream™ is ideal for patients who need fast, targeted migraine relief without taking oral medication. Perfect for those who experience sensitivity to pills, digestive discomfort, or prefer a topical solution for pain management.

targeted relief No pills
Woman face

Real results from real patients

I suffer from severe migraines and nausea, so finding this cream was a lifesaver. The pain relief and soothing effect are fast!
Verified customer
This cream works wonders! It quickly numbs the pain and eases nausea, making it so much easier to get through the day.
Verified customer
MigraCream™ is my go-to for migraines. It provides fast relief, and I can use it without having to worry about taking pills.
Verified customer
Anti-inflammatory Fast acting Precise numbingAnti-inflammatory Fast acting Precise numbing

TRIPLE ACTION, topical application

Anti-inflammatoryFast actingPrecise numbing

  • Ketoprofen (1%) concentrates in the local tissue and blocks the key molecules responsible for inflammation and pain.
  • Lidocaine (4%) provides immediate relief by blocking sodium channels in nerve endings.
  • Metoclopramide (0.5%) serves a dual purpose: it acts as a penetration enhancer and has local anti-nausea effects through its action on dopamine receptors.

The MigraCream™ Difference

MigraCream™
Other medications

Benefits

MigraCream™

Other medications

Direct Pain Relief

Penetrates the skin for targeted action
Must pass through the digestive system first

No Swallowing Required

Easy-to-apply topical formula
Requires taking pills, which some find difficult

Rapid Absorption

Begins working immediately at the site of pain
Delayed onset due to digestion

Stomach-Friendly

Bypasses the gastrointestinal tract
May cause nausea, irritation, or stomach discomfort

The Science Behind MigraCream™

Clinically Proven Relief

Clinically Proven Relief

72% of patients reported significant pain reduction within 60 minutes compared to 35% with placebo.

Fast-Acting, Targeted Formula

Fast-Acting, Targeted Formula

Absorbs through the skin, delivering medication directly to affected areas for faster relief than oral medications.

Gentler on the Stomach

Gentler on the Stomach

Bypassing the digestive system helps avoid nausea, acid reflux, and other gastrointestinal side effects.

Pharmaceutical-Grade

Pharmaceutical-Grade

Manufactured in a certified compounding pharmacy with precisely dosed, high-quality ingredients.

How Hedfirst works
How Hedfirst works

How Hedfirst works

  • 1

    Convenient online intake

    Answer some questions about your health history, 100% online.

  • 2

    US-licensed healthcare providers

    Get a clinical review and prescription sent direct to you.

  • 3

    Migraine specialist compounds

    Receive proven migraine medications backed by decades of research.

  • 4

    Free shipping & support

    You are only charged for medications and providers visit. No hidden fees.

MigraCream™ Frequently Asked Questions

Not finding what you're looking for? Reach to our customer care team.

MigraCream™ is a topical treatment specifically designed to provide fast, effective relief from migraine pain, inflammation, and nausea through absorption into the skin.
MigraCream™ combines ketoprofen, lidocaine, and metoclopramide to target pain, reduce inflammation, and ease nausea directly through the skin. It provides fast relief and long-lasting comfort.
Yes, MigraCream™ requires a prescription. You can consult with a healthcare provider online to receive approval for your treatment.
Many users experience relief within 30 minutes of applying MigraCream™. However, the time it takes for full relief can vary depending on individual response.
MigraCream™ is especially effective for migraines accompanied by nausea or moderate to severe pain. It may not be suitable for all types of headaches. Consult with your healthcare provider to determine if it's right for you.
As with any medication, side effects are possible. Some users may experience skin irritation or allergic reactions. If you experience any adverse effects, discontinue use and consult your healthcare provider.
Yes, MigraCream™ can be used alongside other migraine treatments, but you should always consult your healthcare provider before combining medications. Additionally, avoid using multiple topical products on the same area to prevent skin irritation.
MigraCream™ offers a unique approach by providing fast relief through topical application, avoiding the digestive system. This can be particularly beneficial when nausea prevents taking oral medications.