ZolmEase™ Migraine + Nausea

Dissolvable Tablets

ZolmEase™ Migraine + Nausea

Fast migraine relief plus nausea control in one dissolving tablet.

A specialized dual-action migraine treatment combining powerful headache relief (Zolmitriptan) with targeted nausea control (Ondansetron) in a convenient oral dissolving tablet. Designed specifically for migraine sufferers who experience significant nausea, this innovative formulation dissolves quickly on the tongue - no water needed. Each tablet contains precisely dosed medication to address both pain and nausea simultaneously.

Ingredients dosages:

Zolmitriptan 2.5mg + Ondansetron 4mg

Zolmitriptan 4.5mg + Ondansetron 4mg

Quantity:

Supply:

Total

$0.00

If you aren’t sure about dosages, make a selection and your provider will help you during the consultation. You won’t be charged for your treatment unless approved by your provider. There is a one-time, non-refundable charge for the provider consultation.

Key Ingredients

Zolmitriptan 2.5/4mgOndansetron 4mg

ZolmEase™ delivers powerful migraine relief while preventing nausea, so you can stop your headache without upsetting your stomach. Designed specifically for migraine sufferers who experience significant nausea, this innovative formulation dissolves quickly on the tongue. Each tablet contains precisely dosed medication to address both pain and nausea simultaneously.

The doctor says...

ZolmEase™ offers a game-changing approach to migraine relief by combining Zolmitriptan with Ondansetron in a dissolvable tablet. This innovative formula ensures rapid absorption, even when nausea makes swallowing difficult. By addressing both migraine pain and nausea simultaneously, ZolmEase™ provides more effective and consistent relief, helping patients regain control faster.

Dr. Alexander Mauskop

Hedfirst Chief Medical Advisor

Director, New York Headache Center, Professor of Clinical Neurology, SUNY Downstate Medical Center

Who is ZolmEase™ for?

ZolmEase™ is specifically designed for migraine sufferers who experience significant nausea with their attacks and want fast, reliable relief without needing water. The oral dissolving format makes it ideal for those who have difficulty swallowing pills when nauseated, travel frequently, or simply prefer the convenience of a single medication that addresses both pain and nausea simultaneously.

Migraine relief Nausea control Fast-dissolving

Real results from real patients

I no longer have to plan my day around migraines. This combination helps me stay on track without interruptions.

Verified customer

Fast relief! Within an hour, I feel better, and I don’t have to worry about migraines returning later.

Verified customer

Finally, a migraine medication that actually works. I used to take multiple pills, but this keeps the pain away.

Verified customer

Pain relief Nausea control Fast absorption

DUAL-ACTION, RAPID RELIEF

Pain reliefNausea controlFast absorption

Zolmitriptan (2.5mg) constricts blood vessels and blocks pain signals, targeting migraine pain at its source for rapid relief.
Ondansetron (4mg) prevents nausea and vomiting by blocking serotonin receptors, reducing discomfort during attacks.
The fast-dissolving formula bypasses digestion, ensuring quick absorption and effectiveness even when nausea is present.

The ZolmEase™ Difference

Benefits

ZolmEase™

Other medications

Dual-Action Relief

Combines migraine pain relief with targeted nausea control

Typically addresses only pain

Dissolvable Tablet

Melts on the tongue—no water needed

Requires swallowing with water

Faster Relief

Absorbs quickly for rapid migraine and nausea relief

Delayed effectiveness due to digestion

Comprehensive Symptom Control

Prevents nausea while stopping migraines

May not address nausea

The Science Behind ZolmEase™

15 Minutes Rapid Onset

Starts working in as little as 15 minutes, bypassing digestion for faster relief.

Clinically better than placebo

2.5mg zolmitriptan provides pain relief in 63% of patients within 2 hours.

Effective nausea control

Bypassing the digestive system helps avoid nausea, acid reflux, and other gastrointestinal side effects.

Easier to take

Dissolves instantly on the tongue—no water needed, ideal for travel and pill aversion.

How Hedfirst works

1
Convenient online intake
Answer some questions about your health history, 100% online.
2
US-licensed healthcare providers
Get a clinical review and prescription sent direct to you.
3
Migraine specialist compounds
Receive proven migraine medications backed by decades of research.
4
Free shipping & support
You are only charged for medications and providers visit. No hidden fees.

ZolmEase™ Frequently Asked Questions

Not finding what you're looking for? Reach to our customer care team.

ZolmEase™ is a compounded medication that combines Zolmitriptan (2.5mg) and Ondansetron (4mg) in one convenient oral dissolving tablet for fast-acting relief of both migraine pain and associated nausea.

ZolmEase™ works through a dual-action approach. The zolmitriptan component targets migraine pain by constricting blood vessels and blocking pain signals in the brain, while ondansetron specifically blocks the chemical signals that cause nausea and vomiting. The oral dissolving format allows for rapid absorption, even during active nausea.

Yes, ZolmEase™ requires a prescription from a licensed healthcare provider. Our telemedicine platform makes it easy to consult with a provider who can determine if ZolmEase™ is right for you.

Patients may begin to experience initial relief from both migraine pain and nausea as quickly as 15-30 minutes after taking ZolmEase™. The oral dissolving format allows for rapid absorption through the mouth's tissues, which can lead to faster onset of action compared to traditional tablets.

ZolmEase™ is particularly effective for migraine sufferers who experience moderate to severe nausea with their attacks. It may be especially beneficial for those who have difficulty taking traditional pills during a migraine or who find their nausea interferes with other medications' effectiveness.

Common side effects may include mild drowsiness, dry mouth, or temporary taste changes from the dissolving tablet. More serious side effects are rare but possible. Your healthcare provider will review your medical history to ensure ZolmEase™ is safe for you, particularly if you have heart conditions or are taking certain antidepressants.

Always inform your healthcare provider about all medications you're taking. ZolmEase™ may interact with certain medications, particularly other serotonin-affecting drugs or anti-nausea medications. Your provider will review your current medications to prevent any potentially harmful interactions.

Unlike traditional migraine medications, ZolmEase™ combines migraine pain relief with powerful anti-nausea medication in a single oral dissolving tablet. This unique format ensures reliable delivery of medication even when swallowing pills is difficult due to nausea.